Which of the following is a common cause of uterine cancer?

Obesity and smoking are recognized as significant risk factors for uterine cancer. Obesity leads to higher levels of estrogen in the body, primarily due to increased adipose tissue, which converts androgens into estrogens. This excess estrogen can promote the development of uterine lining (endometrium) abnormalities, potentially leading to cancer. Additionally, smoking is linked to various cancers, including endometrial cancer, as it contributes to the overall risk and may induce changes in hormonal pathways.

Understanding the relationship between these factors and the development of uterine cancer highlights the importance of addressing lifestyle aspects in both prevention and management strategies. Addressing obesity and smoking can markedly reduce the risk of developing this type of cancer.