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In a patient with a history of angioedema, which parts of the body are most likely to be affected?

  1. Isolated to the colon.

  2. Anywhere in the enteral tract.

  3. Chest.

  4. Face and Lips.

The correct answer is: Face and Lips.

In cases of angioedema, the areas most commonly affected are the face and lips. This swelling is due to an increase in vascular permeability leading to localized edema, and it often occurs in regions where subcutaneous tissue is more lax, such as around the eyes, mouth, and lips. Swelling in these areas can be particularly alarming due to the visibility and potential for airway obstruction, especially if it extends to the throat. Angioedema can also occur in other parts of the body, but the facial areas are classic manifestations that healthcare professionals typically monitor closely for complications. While angioedema can potentially involve other areas of the body, options referring to the colon or chest are less characteristic and not typically associated with the primary symptoms of angioedema. The enteral tract may not experience the same degree of localized swelling as seen in the facial regions. Therefore, the most relevant and critical areas of concern in this condition are indeed the face and lips.