CEA Nursing Practice Exam

In patients with asthma, what classification of drugs should not be used alone?

1. Corticosteroids

2. Long acting beta agonists

3. Leukotriene antagonists

4. Short acting beta agonists

The correct answer is: Long acting beta agonists

Long-acting beta agonists (LABAs) should not be used alone in the management of asthma due to the potential risk of serious adverse outcomes, including increased mortality associated with asthma exacerbations. LABAs are effective bronchodilators that provide prolonged relief of bronchoconstriction, but they do not address the underlying inflammation characteristic of asthma. To ensure optimal control of asthma symptoms, LABAs must always be combined with inhaled corticosteroids (ICS), which target the underlying inflammation and help to reduce acute exacerbations. This combination improves overall control of asthma symptoms and decreases the likelihood of severe attacks. Using LABAs alone can mask the underlying inflammation, leading to a dangerous delay in appropriate treatment for an exacerbation, ultimately compromising patient safety. The other classifications of drugs have different roles in asthma management. Corticosteroids are effective anti-inflammatories and can be used alone for mild persistent asthma, while leukotriene antagonists can also be part of a treatment plan but may be used alone in some cases. Short-acting beta agonists (SABAs) are typically used as rescue medications for immediate relief of acute symptoms, so they are meant for intermittent use rather than continuous management. Thus, the unique role and risks associated with LAB